Swiftly Meds Private Limited

Temolon 100 mg Capsules (Temozolomide) - Medicine Description

Brand Name: Temolon
Generic Name: Temozolomide
Strength: 100 mg
Form: Capsule
Therapeutic Class: Antineoplastic (Chemotherapy Agent), Alkylating Agent

Overview:

Temolon 100 mg Capsules contain Temozolomide, a chemotherapy drug classified as an alkylating agent. It is primarily used to treat glioblastoma multiforme (GBM), one of the most aggressive forms of brain cancer, and anaplastic astrocytoma (AA). Temozolomide is effective in treating these cancers because it can cross the blood-brain barrier, which is a challenge for many other chemotherapy drugs. It works by interfering with the DNA of cancer cells, preventing their replication and leading to their destruction.

Temozolomide is often prescribed in combination with radiation therapy for newly diagnosed patients or as a standalone treatment for recurrent cases of glioblastoma. It is also indicated for patients who experience disease progression after initial treatment with other chemotherapy agents.

Mechanism of Action:

Temozolomide is an oral alkylating agent that works by adding alkyl groups to the DNA of cancer cells. These alkyl groups cause the DNA strands to break, resulting in damage that prevents the cancer cells from replicating. This disruption of DNA leads to cell death.

Temozolomide is metabolized in the body into the active metabolite MTIC (monomethyl-triazeno-imidazole-carboxamide), which is responsible for its antitumor effects. Because it crosses the blood-brain barrier, it is particularly effective in treating brain tumors such as glioblastoma multiforme and anaplastic astrocytoma.

Indications:

Temolon 100 mg Capsules (Temozolomide) are indicated for the treatment of:

1. Glioblastoma Multiforme (GBM):

   • As an adjunct to radiation therapy for newly diagnosed glioblastoma multiforme (GBM).
   • As a monotherapy for the treatment of recurrent glioblastoma, in patients who have previously been treated with surgery and radiation.

2. Anaplastic Astrocytoma (AA):

   • For anaplastic astrocytoma (AA) in adults who have shown disease progression after standard chemotherapy. This may be used as a second-line treatment after other therapies have failed.

Dosage and Administration:

The recommended dosage of Temolon 100 mg Capsules (Temozolomide) varies based on the disease being treated and whether it is used in combination with radiation therapy.

For Glioblastoma Multiforme (GBM):

1. Initial Treatment (with Radiation Therapy):

   • Dose: 75 mg/m² once daily for 42 consecutive days, starting on the first day of radiation therapy.
   • After the 42-day course of radiation therapy, the maintenance dose is typically 150 mg/m² for 5 consecutive days during a 28-day cycle. This can be adjusted based on the patient’s response and tolerance.

2. Maintenance Treatment (Post-Radiation Therapy):

   • Dose: After radiation therapy, Temolon is typically continued at a dose of 150–200 mg/m² once daily for 5 consecutive days during each 28-day cycle. This is generally continued until disease progression is noted.

For Anaplastic Astrocytoma (AA):

• Dose: The starting dose is typically 150 mg/m² once daily for 5 days during a 28-day cycle. Depending on how the patient responds, the dose may be increased to 200 mg/m² for subsequent cycles.

 

Capnat 500 mg Tablets contain Capecitabine, an oral chemotherapy drug used to treat various cancers, including breast cancer, colorectal cancer, and gastric cancer. Capecitabine is a prodrug that is converted into 5-fluorouracil (5-FU) in the body, a substance that inhibits cancer cell growth by interfering with DNA synthesis.

Generic Name:

• Capecitabine (Brand name: Capnat)

Uses:

• Breast Cancer: Capnat is used to treat early-stage and metastatic breast cancer, either alone or in combination with other chemotherapy drugs.
• Colorectal Cancer: Capnat is prescribed for metastatic colorectal cancer and can be used with other chemotherapy agents like oxaliplatin.
• Gastric Cancer: Capecitabine is used in the treatment of gastric cancer (stomach cancer), often in combination with other chemotherapy drugs.
• Adjuvant Therapy: Capnat can also be used as adjuvant therapy (additional treatment after surgery) to reduce the risk of recurrence, particularly in breast and colorectal cancers.

Benefits:

• Convenient Oral Formulation: Capnat offers the convenience of an oral form, eliminating the need for intravenous injections, making it easier for patients to manage their treatment at home.
• Versatility: It is effective against several types of cancer, including breast, colorectal, and gastric cancers.
• Combination Therapy: Often used with other chemotherapy drugs, Capnat enhances treatment effectiveness and may improve patient outcomes.

Dosage and How to Take:

• Standard Dose: The typical dose of Capnat 500 mg is based on the patient’s body surface area (BSA). The usual regimen is 1250 mg/m² twice daily for 14 days, followed by a 7-day break, forming a 21-day cycle. Dosage may vary depending on the type of cancer and patient response.
• How to Take: Take the tablets with food to reduce the risk of stomach upset. Swallow the tablets whole with a glass of water. Do not crush, chew, or break the tablet.
• Missed Dose: If you miss a dose, take it as soon as possible, unless it's close to the time for your next dose. Do not double the dose to make up for a missed one.

Storage:

• Conditions: Store Capnat 500 mg Tablets at room temperature (15°C to 30°C or 59°F to 86°F).
• Keep the tablets in a dry, cool place, away from light, heat, and moisture.
• Keep out of the reach of children.

Side Effects:

• Common Side Effects:
  • Gastrointestinal Issues: Nausea, vomiting, diarrhea, and stomach pain are common. Taking Capnat with food can help alleviate these effects.
  • Hand-Foot Syndrome (Palmar-Plantar Erythrodysesthesia): Redness, swelling, and pain on the hands or feet.
  • Fatigue: Many patients report feeling tired or weak.
  • Loss of Appetite and Weight Loss: Some may experience a reduced appetite, which may lead to weight loss.
  • Mouth Sores: Painful sores or ulcers in the mouth can develop.
  • Hair Loss: Hair thinning or hair loss may occur, though it is typically temporary.
  • Liver Toxicity: Capecitabine may increase liver enzyme levels, so regular liver function tests are necessary.
  • Increased Infection Risk: Capecitabine can lower white blood cell counts, making patients more susceptible to infections.

Bosutris 400 mg Tablets - Description

Bosutris 400 mg Tablets contain Bosutinib, a tyrosine kinase inhibitor (TKI) used in the treatment of chronic myelogenous leukemia (CML) in adults. It is specifically indicated for patients who are resistant or intolerant to previous treatments such as imatinib, dasatinib, or nilotinib. Bosutinib works by inhibiting the BCR-ABL fusion protein, a key driver of CML, thereby interfering with the abnormal signaling pathways that lead to uncontrolled cell growth in the bone marrow.

Mechanism of Action: Bosutris (Bosutinib) targets and inhibits specific kinases involved in the growth of cancerous cells in CML, especially the BCR-ABL protein. This fusion protein is formed due to a chromosomal translocation and is responsible for the uncontrolled proliferation of leukemic cells. By blocking the action of this protein, Bosutris helps to reduce the number of leukemia cells and prevent disease progression.

Indications: Bosutris 400 mg Tablets are indicated for the treatment of:

• Chronic Myelogenous Leukemia (CML): Bosutris is used in adult patients with chronic phase CML who are resistant or intolerant to prior therapy with other tyrosine kinase inhibitors like imatinib, dasatinib, or nilotinib.

Dosage:

• The recommended starting dose of Bosutris is 400 mg once daily, taken orally with food.
• The dose may be adjusted based on tolerability, with a maximum dose of 500 mg daily.
• It is important to take Bosutris consistently at the same time each day for optimal results. The tablet should be swallowed whole and should not be split, crushed, or chewed.

Side Effects: Common side effects of Bosutris include:

• Diarrhea
• Nausea
• Fatigue
• Decreased appetite
• Headache Serious side effects may include:
• Liver problems (e.g., elevated liver enzymes, jaundice)
• Low blood cell counts (e.g., neutropenia, thrombocytopenia, anemia)
• Pulmonary (lung) issues, such as shortness of breath or cough
• Gastrointestinal bleeding or ulcers

Precautions:

• Liver function: Bosutris may cause liver toxicity. Regular liver function tests are recommended before and during treatment.
• Blood counts: Bosutris may cause a decrease in white blood cells, red blood cells, and platelets, leading to an increased risk of infection, anemia, or bleeding. Regular blood tests should be monitored.
• Drug interactions: Inform your healthcare provider of all other medications, including over-the-counter drugs, as Bosutris may interact with certain medications, especially those affecting liver enzymes.
• Pregnancy and breastfeeding: Bosutris is not recommended during pregnancy and breastfeeding unless the benefits outweigh the risks. Consult a healthcare provider for alternatives if pregnant or breastfeeding.

Storage: Store Bosutris 400 mg Tablets at room temperature, away from moisture and heat. Keep out of reach of children.

Conclusion: Bosutris 400 mg Tablets provide an effective treatment option for adults with chronic myelogenous leukemia (CML) who have not responded well to previous therapies. By inhibiting the BCR-ABL protein, Bosutris helps control the progression of the disease and improves survival rates in patients with resistant or intolerant CML. As with all medications, regular monitoring for side effects and blood counts is essential for safe and effective use.

Apnat 60 mg Tablets - Description

Apnat 60 mg Tablet is a prescription medication used for managing and treating specific medical conditions, primarily Type 2 Diabetes Mellitus. It contains Empagliflozin, an active ingredient that belongs to a class of drugs known as Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. Apnat works by helping the kidneys remove glucose from the bloodstream through urine, thereby lowering blood sugar levels in people with type 2 diabetes.

Key Features:

• Generic Name: Empagliflozin
• Brand Name: Apnat
• Strength: 60 mg
• Form: Oral Tablets
• Therapeutic Class: SGLT2 Inhibitor
• Manufacturer: [Manufacturer Name, if applicable]

Mechanism of Action:

Apnat works by inhibiting the SGLT2 protein in the kidneys, which is responsible for reabsorbing glucose back into the bloodstream from the urine. By blocking this protein, Apnat helps promote the excretion of excess glucose through the urine, thus helping to reduce blood sugar levels in patients with type 2 diabetes. This action also aids in weight loss and may help lower blood pressure.

Indications:

• Type 2 Diabetes Mellitus: Apnat is used alongside diet and exercise to improve blood sugar control in adults with type 2 diabetes.
• Cardiovascular Benefits: Apnat has also been shown to reduce the risk of cardiovascular events, such as heart attack, stroke, and hospitalization due to heart failure in patients with type 2 diabetes and established cardiovascular disease.
• Chronic Kidney Disease (CKD): Empagliflozin may also be prescribed in some cases for patients with chronic kidney disease and is beneficial in reducing the progression of kidney function decline.

Dosage and Administration:

• The typical dosage of Apnat is 60 mg once daily, taken with or without food.
• The tablet should be swallowed whole with a glass of water.
• The dose may be adjusted based on the patient's condition and response to the medication, and it’s crucial to follow the healthcare provider’s instructions.

Side Effects:

Like any medication, Apnat may cause some side effects, though not everyone will experience them. Common side effects include:

• Urinary tract infections
• Increased urination
• Low blood pressure (hypotension)
• Dehydration
• Dizziness
• Fatigue

Serious but rare side effects may include:

• Kidney problems (such as acute kidney injury)
• Ketoacidosis (a serious condition that can occur when the body produces high levels of ketones)
• Allergic reactions, including skin rash or swelling.

It is essential to consult a healthcare provider before starting Apnat, especially for individuals with a history of kidney problems, dehydration, or electrolyte imbalances.

Precautions and Warnings:

• Kidney Function: Patients with impaired kidney function should use Apnat with caution. Regular monitoring of kidney function is recommended.
• Pregnancy and Breastfeeding: Apnat is not recommended during pregnancy or while breastfeeding unless specifically prescribed by a healthcare provider.
• Hypotension: Apnat can cause low blood pressure, particularly in patients who are volume-depleted or on diuretics.

Storage:

Store Apnat tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.

Livonibe 200 mg Tablets – Product Description

Generic Name: Lenvatinib
Brand Name: Livonibe
Strength: 200 mg
Form: Oral tablet

Introduction: Livonibe 200 mg Tablet is an advanced medication primarily used in the treatment of various cancers. Its active ingredient, Lenvatinib, belongs to the class of drugs called tyrosine kinase inhibitors (TKIs), which work by blocking certain proteins that promote the growth and spread of cancer cells. Livonibe has been clinically proven to be effective in managing several types of cancer, including thyroid cancer, hepatocellular carcinoma (HCC), and renal cell carcinoma (RCC).

Indications: Livonibe 200 mg is prescribed for the treatment of:

1. Differentiated Thyroid Cancer (DTC): For patients with radioactive iodine-refractory differentiated thyroid cancer.
2. Hepatocellular Carcinoma (HCC): A form of liver cancer.
3. Renal Cell Carcinoma (RCC): Kidney cancer, especially in combination with other therapies.
4. Endometrial Carcinoma: In cases where the cancer has spread or cannot be surgically removed.

Dosage and Administration:

• Recommended Dose: The usual recommended dose of Livonibe is 200 mg, taken orally once daily.
• Administration: Take the tablet with or without food. It is essential to swallow the tablet whole with water and not crush or chew it.
• Adjustment: Depending on tolerance and side effects, the dosage may be adjusted by the prescribing doctor. Regular monitoring is required to check for adverse effects.
• Missed Dose: If you miss a dose, take it as soon as you remember. If it is nearly time for the next dose, skip the missed dose. Do not take two doses at once to make up for a missed dose.

Side Effects: Common side effects include:

• Fatigue
• Diarrhea
• Hypertension (high blood pressure)
• Nausea and vomiting
• Loss of appetite and weight loss
• Stomatitis (mouth sores)
• Hand-foot syndrome (pain, redness, and swelling on hands and feet)

Serious side effects, though less common, may include:

• Severe liver problems (indicated by yellowing of the skin/eyes, dark urine)
• Heart problems (chest pain, shortness of breath)
• Severe bleeding
• Gastrointestinal perforation
• Thyroid problems (especially in thyroid cancer treatment)
• Severe high blood pressure (hypertensive crisis)

Patients are advised to report any unusual side effects to their healthcare provider promptly.

Precautions: Before taking Livonibe, inform your doctor if you have:

• A history of heart disease or hypertension
• Liver or kidney problems
• Gastrointestinal disorders
• Allergies to any components of the medication
• Pregnancy or breastfeeding status

Pregnancy Category: Livonibe is classified as a Category D drug (positive evidence of human fetal risk). It should not be used during pregnancy unless absolutely necessary. Effective contraception should be used during treatment.

Drug Interactions:

• CYP3A4 Inhibitors/Inducers: Livonibe metabolism can be altered by drugs that inhibit or induce the CYP3A4 enzyme.
• Anticoagulants: There may be an increased risk of bleeding when used in combination with blood thinners.

Storage:

• Store Livonibe tablets in a cool, dry place at room temperature (15°C to 25°C).
• Keep the medication away from direct sunlight and moisture.
• Keep out of reach of children.

Tipanat 20 mg Tablets – Product Description

Generic Name: Tipranavir
Brand Name: Tipanat
Strength: 20 mg
Form: Tablet

Introduction:
Tipanat 20 mg is a prescription medication primarily used in the treatment of Human Immunodeficiency Virus (HIV) infection. It contains Tipranavir as its active ingredient, an antiretroviral drug from the protease inhibitor (PI) class, which plays a crucial role in the management of HIV.

Mechanism of Action:
Tipranavir works by inhibiting the activity of the HIV protease enzyme. The HIV protease is essential for the virus to replicate and mature. By inhibiting this enzyme, Tipranavir prevents the virus from multiplying, thus reducing the viral load in the body and helping to maintain a healthier immune system.

Indications:

• HIV Infection: Tipnat 20 mg is used as part of a combination antiretroviral therapy (ART) regimen to treat HIV-1 infection in both treatment-naive and treatment-experienced adults and pediatric patients.
• HIV Resistance: Tipranavir is often recommended for patients who have developed resistance to other protease inhibitors.

Dosage and Administration:

• Adult Dosage: The typical dose for adults is 500 mg (25 mg per tablet) twice a day, when used in combination with other antiretroviral agents. The dosage may vary based on individual medical conditions and the presence of any coexisting conditions.
• Pediatric Dosage: The dosage for children is based on body weight and should be carefully prescribed by a healthcare provider.
• Tipnat 20 mg tablets are taken orally, with or without food. For optimal effect, they should be taken as part of a prescribed combination therapy.

Contraindications:

• Hypersensitivity: Tipnat should not be used by patients who are allergic to Tipranavir or any of its components.
• Liver Disorders: Patients with severe hepatic impairment or liver diseases should avoid using Tipnat, as the drug is metabolized in the liver and could worsen liver function.
• Pregnancy: Pregnant women should only use Tipnat if absolutely necessary, and under the supervision of a healthcare provider.

Side Effects:
Like all medications, Tipnat 20 mg may cause side effects, although not everyone experiences them. Common side effects include:

• Nausea
• Diarrhea
• Headache
• Fatigue
• Abdominal pain

Serious side effects, though rare, may include:

• Liver damage (hepatotoxicity)
• Skin rashes or allergic reactions
• Bleeding in patients with hemophilia
• Changes in fat distribution (lipodystrophy)

Patients should contact their doctor immediately if any serious side effects are observed.

Precautions:

• Liver Function: Regular liver function tests are advised as Tipnat can affect the liver.
• Drug Interactions: Tipranavir can interact with several medications, including those used for epilepsy, tuberculosis, and cardiovascular conditions. It’s essential to inform your doctor about all medications you are currently taking, including over-the-counter drugs and supplements.
• Kidney and Heart Disease: Caution is required when prescribing Tipnat for individuals with pre-existing kidney or heart conditions.

Storage:
Store Tipnat 20 mg tablets at room temperature, away from heat, moisture, and direct light. Keep out of the reach of children.

Axzyb 5mg Tablets (Axitinib)

Description: Axzyb 5mg tablets contain Axitinib as the active ingredient. Axitinib is an oral kinase inhibitor primarily used in the treatment of certain types of cancer, particularly renal cell carcinoma (RCC). It works by inhibiting specific enzymes (tyrosine kinases) involved in the growth and spread of cancer cells, helping to slow down or stop the cancer's progression.

Indications:

• Renal Cell Carcinoma (RCC): Axitinib is mainly used for the treatment of advanced or metastatic renal cell carcinoma, either as a monotherapy or in combination with other cancer treatments.

• It may also be used in other cancers, depending on a healthcare provider’s assessment.

Mechanism of Action: Axitinib inhibits multiple vascular endothelial growth factor (VEGF) receptors and other kinases, which are involved in the formation of new blood vessels (angiogenesis) that supply tumors. By blocking these pathways, Axitinib reduces tumor blood supply, thereby inhibiting tumor growth and metastasis.

Dosage:

• Starting Dose: Typically, the recommended dose for Axitinib is 5 mg taken twice daily, but the exact dosage may vary depending on individual factors, including tolerance and response to the treatment.

• Dose Adjustment: Your doctor may adjust the dose based on side effects or the severity of the disease. The dose may be increased or decreased depending on your response to treatment.

Side Effects:

• Common Side Effects: Fatigue, diarrhea, high blood pressure, decreased appetite, nausea, and weight loss.

• Serious Side Effects: High blood pressure, bleeding, heart problems, kidney problems, and gastrointestinal perforation.

• Rare but serious side effects may include thyroid issues or liver dysfunction.

Precautions:

• Not recommended for pregnant women due to potential harm to the fetus.

• Patients should be monitored for high blood pressure, as Axitinib can increase blood pressure.

• Kidney function should be monitored, especially in those with pre-existing renal issues.

• Liver function may also need to be monitored during treatment.

• Consult your healthcare provider if you are planning to get pregnant, are breastfeeding, or have any other serious health conditions (like bleeding disorders or gastrointestinal issues).

Storage:

• Temperature: Store Axzyb tablets at room temperature (between 15°C to 30°C or 59°F to 86°F).

• Moisture and Light: Keep the medication in a dry place, away from excessive moisture and light.

• Childproof: Keep out of reach of children to avoid accidental ingestion.

• Expiration: Do not use Axzyb tablets after the expiration date marked on the packaging.

Spnib 20mg Tablets (Dasatinib)

Description: Spnib 20mg Tablets contain Dasatinib, an oral tyrosine kinase inhibitor (TKI) used to treat specific types of cancers, particularly Chronic Myelogenous Leukemia (CML) and Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL). Dasatinib works by inhibiting the activity of several key proteins, specifically the BCR-ABL1 fusion protein, which is responsible for the abnormal growth of leukemia cells in CML and Ph+ ALL. By blocking the signals that lead to uncontrolled cancer cell division, Dasatinib can slow or stop the growth of these cancer cells.

Indications:

• Chronic Myelogenous Leukemia (CML): Dasatinib is primarily used for treating CML, particularly in patients who have developed resistance or intolerance to Imatinib, another commonly used TKI.

• Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL): Dasatinib is used to treat Ph+ ALL, an aggressive form of leukemia characterized by the presence of the Philadelphia chromosome.

• Other cancers: Dasatinib may be used in the treatment of other malignancies, depending on the patient's condition and the doctor's clinical decision.

Mechanism of Action: Dasatinib is a multi-targeted tyrosine kinase inhibitor that works by blocking the activity of several important proteins involved in cancer cell growth, such as:

• BCR-ABL1: The abnormal fusion protein formed by the Philadelphia chromosome, a genetic mutation that drives the growth of CML and Ph+ ALL cells.

• SRC family kinases, c-Kit, and PDGFR: Other kinases that promote tumor growth and survival. By inhibiting these proteins, Dasatinib prevents cancer cells from growing and dividing.

Dosage:

• Typical Dose: The usual starting dose for Spnib 20mg Tablets (Dasatinib) is 20 mg once daily for patients with CML or Ph+ ALL, though the dose may be adjusted based on the patient's response and tolerance to the drug.

• Administration: Take the tablet once a day, with or without food, and swallow the tablet whole with a full glass of water. Do not chew, crush, or break the tablet.

• Missed Dose: If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Do not take two doses at once.

Side Effects: Common side effects of Spnib 20mg Tablets (Dasatinib) include:

• Fatigue

• Headache

• Diarrhea

• Nausea

• Rashes

• Muscle or joint pain

• Low blood cell counts (which may lead to an increased risk of infections, bleeding, or anemia)

Serious side effects include:

• Pleural effusion (fluid buildup around the lungs), which can cause shortness of breath or chest pain.

• Liver toxicity: Signs include jaundice (yellowing of the skin or eyes), dark urine, or abdominal pain.

• Cardiovascular problems: Including heart failure or abnormal heart rhythms.

• Severe bleeding: Unusual bruising or bleeding, including blood in the stool or urine.

• Pulmonary arterial hypertension (PAH): High blood pressure in the arteries that supply the lungs.

Afzanna 20mg Tablets (Afatinib)

Description: Afzanna 20mg Tablets contain Afatinib, a tyrosine kinase inhibitor (TKI), primarily used to treat non-small cell lung cancer (NSCLC) and other cancers that involve mutations in the epidermal growth factor receptor (EGFR) gene. Afatinib works by inhibiting the activity of the EGFR family of receptors, which play a key role in cancer cell growth and survival. By blocking these receptors, Afatinib helps to slow down the growth of cancer cells, shrink tumors, and potentially improve survival in patients with EGFR-positive tumors.

Indications:

• Non-Small Cell Lung Cancer (NSCLC): Afzanna is used for the treatment of advanced or metastatic NSCLC in patients whose tumors are EGFR-positive, particularly when there are mutations that are sensitive to EGFR inhibitors like Afatinib.

• Squamous Cell Carcinoma of the Lung: It may also be used for patients with advanced or metastatic squamous cell carcinoma of the lung who have not responded well to chemotherapy.

• Other EGFR-mutated cancers: In some cases, Afatinib may be used off-label for cancers that express EGFR mutations or other related receptors.

Mechanism of Action: Afatinib is an irreversible tyrosine kinase inhibitor that blocks the activation of several receptors in the EGFR family, including:

• EGFR (HER1)

• HER2

• HER3

• HER4

These receptors are often overexpressed or mutated in various cancers, leading to abnormal cell growth and division. Afatinib binds irreversibly to these receptors and prevents their activation, helping to slow tumor growth and the spread of cancer.

Dosage:

• Typical Dose: The usual starting dose for Afzanna 20mg Tablets is 20 mg once daily. The dose may be adjusted based on the patient's response to treatment and any side effects they experience.

• Administration: Take Afzanna 20mg Tablets once daily at the same time each day. The tablet can be taken with or without food. Swallow the tablet whole with a glass of water—do not chew, crush, or break the tablet.

• Missed Dose: If you miss a dose, take it as soon as you remember unless it’s almost time for the next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.

Side Effects: Common side effects of Afzanna 20mg Tablets may include:

• Diarrhea: One of the most frequent and severe side effects. It’s important to manage diarrhea promptly to prevent dehydration.

• Skin Rash: Acne-like rashes or dry, irritated skin are common. These may improve over time, but they can sometimes be severe.

• Mouth sores or ulcers: Painful sores in the mouth are a common side effect.

• Fatigue: Feeling tired or weak is commonly reported.

• Loss of appetite or weight loss.

• Nausea or vomiting.

• Nail changes: Discoloration or brittleness of nails may occur in some patients.

Serious side effects may include:

• Lung problems: Symptoms like shortness of breath, a persistent cough, or chest pain could indicate interstitial lung disease (ILD), a serious side effect that requires immediate medical attention.

• Liver toxicity: Symptoms such as jaundice (yellowing of the skin or eyes), dark urine, or upper abdominal pain may indicate liver damage.

Tacrotreat 0.5 mg Capsules

Composition: Each capsule of Tacrotreat contains 0.5 mg of Tacrolimus as the active ingredient. The capsule also includes excipients for its formulation.

Pharmacological Category: Tacrolimus is an immunosuppressive agent primarily used in preventing organ rejection after transplant surgery, as well as in the treatment of certain autoimmune diseases.

Mechanism of Action: Tacrolimus works by inhibiting T-cell activation through the suppression of calcineurin activity, a key enzyme in the activation of T-cells. This results in the suppression of the immune system, which helps prevent the rejection of transplanted organs or control autoimmune activity.

Indications:

• Organ Transplantation: Tacrolimus is commonly prescribed to prevent organ rejection in patients who have received kidney, liver, heart, and other solid organ transplants.

• Autoimmune Diseases: It may also be used in certain severe autoimmune conditions, including nephrotic syndrome and dermatitis, where immune suppression is necessary.

Dosage and Administration: Tacrotreat 0.5 mg capsules are typically prescribed for oral administration. The dosage depends on the specific condition being treated, the patient's age, and body weight. Dosages are usually adjusted to maintain specific blood concentration levels to avoid toxicity or inadequate suppression. It is crucial to follow the healthcare provider's instructions for optimal dosing.

Tacrolimus is usually administered twice daily, and it is recommended to take the capsules at the same time each day, preferably on an empty stomach to improve absorption. The capsules should be swallowed whole with a glass of water and should not be crushed or chewed.

Side Effects: Like all medications, Tacrolimus can cause side effects. Common adverse reactions include:

• Kidney Dysfunction (elevated serum creatinine levels)

• Hypertension

• Hyperkalemia (elevated potassium levels)

• Headache

• Tremors

• Nausea or vomiting

• Diarrhea

• Increased risk of infections

Serious but less common side effects include:

• Neurotoxicity (e.g., seizures, confusion)

• Liver dysfunction

• Gastrointestinal bleeding

Patients should be regularly monitored for signs of kidney or liver dysfunction, electrolyte imbalances, and infections.

Precautions:

• Tacrolimus should be used cautiously in patients with a history of renal impairment or liver disorders.

• Patients on Tacrolimus should avoid exposure to live vaccines and seek medical advice before getting vaccinated.

• It is important to avoid grapefruit and grapefruit juice during treatment with Tacrolimus, as these can interfere with its metabolism and increase the risk of side effects.

Contraindications: Tacrolimus is contraindicated in patients with known hypersensitivity to Tacrolimus or any component of the formulation.

Storage: Store Tacrotreat 0.5 mg capsules in a cool, dry place, away from moisture and heat. Keep out of reach of children.

Important Notes:

• Tacrolimus therapy should always be monitored by healthcare professionals with regular blood tests to ensure therapeutic levels and minimize the risk of toxicity.

• Patients should never adjust the dosage without consulting their doctor, as this could lead to organ rejection or adverse effects.

Calutide 50mg Tablets - Product Description

Calutide 50mg Tablets contain Bicalutamide as the active ingredient, a medication used primarily in the treatment of prostate cancer. It is an anti-androgen, which means it works by blocking the action of male hormones (androgens), such as testosterone, in the body. This medication is used in combination with other therapies or on its own in certain treatment regimens to help slow or stop the growth of prostate cancer cells.

Indications: Calutide is primarily prescribed for the treatment of:

• Prostate cancer: It is used in the management of prostate cancer, especially in combination with other drugs like LHRH agonists (Luteinizing Hormone-Releasing Hormone) or after surgery to prevent cancer recurrence.
• Adjuvant treatment: It may be used as an adjunct therapy to help prevent the spread of prostate cancer, especially after surgery or radiation therapy.
• Advanced prostate cancer: It can be used for patients with advanced or metastatic prostate cancer, where the cancer has spread beyond the prostate.

Mechanism of Action: Bicalutamide, the active ingredient, is a selective androgen receptor blocker. It prevents testosterone and other androgens from binding to their receptors on prostate cancer cells. By blocking these hormones, Bicalutamide helps to slow the growth of cancer cells that are dependent on androgenic hormones for growth and proliferation. This leads to a decrease in the size and progression of prostate tumors.

Dosage and Administration: The recommended dose for most adults is 50 mg once daily, typically taken with or without food. It is important to take the tablet at the same time each day to maintain consistent levels of the drug in the body.

Precautions: Before starting Calutide, it is important to inform your doctor if you have:

• A history of liver disease, as liver function may be affected by this medication.
• Allergies to Bicalutamide or any of its inactive ingredients.
• Heart problems, especially since some patients may experience changes in heart rhythm while on this medication.
• Any history of diabetes, as Bicalutamide can sometimes alter glucose metabolism.

Side Effects: Common side effects of Calutide may include:

• Hot flashes
• Weakness or fatigue
• Nausea or vomiting
• Diarrhea
• Decreased libido or sexual dysfunction
• Liver enzyme changes (monitoring may be necessary)

Some serious side effects may include:

• Signs of liver damage (yellowing of the skin/eyes, dark urine, abdominal pain)
• Shortness of breath or chest pain (may indicate heart-related issues)
• Unusual bleeding or bruising

If any severe side effects occur, medical attention should be sought immediately.

Contraindications: Calutide should not be used in:

• Women or children, as it is intended for male patients with prostate cancer.
• Individuals with severe liver impairment or those who have an allergy to Bicalutamide or any of the tablet’s ingredients.

Interactions: Bicalutamide may interact with several other medications, including:

• Anticoagulants (blood thinners)
• Drugs that affect liver enzymes, such as ketoconazole, itraconazole, or rifampicin
• Other cancer therapies, which may require dosage adjustments

It’s crucial to inform your healthcare provider of all medications you are taking to avoid potential interactions.

Storage: Store Calutide 50mg Tablets in a cool, dry place, away from direct sunlight, at room temperature (15-30°C). Keep out of reach of children.

Capeta Nova 500 mg Tablets contain Capecitabine, an oral chemotherapy medication used in the treatment of various cancers, including breast cancer, colorectal cancer, and gastric cancer. Capecitabine is a prodrug, which means it is metabolized into 5-fluorouracil (5-FU) in the body, and 5-FU works by interfering with the synthesis of DNA, inhibiting cancer cell growth.

Generic Name:

• Capecitabine (Brand name: Capeta Nova)

Uses:

• Breast Cancer: Capeta Nova is commonly prescribed for early-stage and metastatic breast cancer. It can be used alone or in combination with other chemotherapy drugs.
• Colorectal Cancer: It is used to treat metastatic colorectal cancer, either alone or combined with other agents like oxaliplatin.
• Gastric Cancer: Capeta Nova is also used in the treatment of gastric cancer (stomach cancer), often as part of combination chemotherapy regimens.
• Adjuvant Therapy: It is used as adjuvant therapy after surgery to reduce the risk of cancer recurrence, particularly for breast cancer and colorectal cancer.

Benefits:

• Oral Administration: One of the main benefits of Capeta Nova is that it is taken orally, making it a more convenient option than intravenous chemotherapy.
• Effective for Multiple Cancer Types: Capecitabine is used to treat several types of cancer, including breast, colorectal, and gastric cancers.
• Combination Therapy: When used in combination with other chemotherapy agents, Capeta Nova can improve the overall effectiveness of cancer treatment.

Dosage and How to Take:

• Standard Dose: The typical dose of Capeta Nova 500 mg Tablets is based on the patient’s body surface area (BSA). The usual dose is 1250 mg/m² twice daily for 14 days, followed by a 7-day rest period. This constitutes a 21-day cycle. Doses may be adjusted based on the patient's response to treatment and the type of cancer.
• How to Take: Take Capeta Nova with food to minimize stomach irritation. Swallow the tablets whole with a full glass of water. Do not crush, chew, or break the tablets.
• Missed Dose: If you miss a dose, take it as soon as you remember unless it is close to the time for the next dose. Do not double the dose to make up for a missed one.

Storage:

• Conditions: Store Capeta Nova 500 mg Tablets at room temperature (15°C to 30°C or 59°F to 86°F), away from heat, moisture, and direct sunlight.
• Keep out of the reach of children.

Side Effects:

Common side effects of Capeta Nova 500 mg Tablets include:

• Gastrointestinal Issues: Nausea, vomiting, diarrhea, and stomach pain are common. Taking the drug with food can help reduce these effects.
• Hand-Foot Syndrome (Palmar-Plantar Erythrodysesthesia): Redness, swelling, and pain on the palms of the hands or soles of the feet.
• Fatigue: Many patients feel tired or weak during treatment.
• Loss of Appetite and Weight Loss: Some patients experience loss of appetite leading to weight loss.
• Mouth Sores: Painful sores or ulcers may develop in the mouth.
• Hair Loss: Temporary hair thinning or hair loss may occur.
• Liver Toxicity: Capecitabine can affect liver function, so liver enzyme levels should be monitored.
• Increased Infection Risk: The medication can lower white blood cell counts, increasing the risk of infections.